Curious about Ketamine: An overview
Ketamine has been around for more than 50 years. But it's newly discovered neuroprotective, anti-inflammatory and anti-tumor effects and the now-known usefulness of low-dose ketamine regimens have helped to expand the clinical application profile of the drug and make it a favorite of users concerned with longevity and optimal wellness.
Ketamine’s history begins with phencyclidine (PCP), which was first synthesized in 1956 by chemists at Parke Davis Company (Maddox et al., 1965) who discovered ketamine’s unique and fascinating pharmacology. A structural analog at one-tenth the potency of its parent drug phencyclidine, ketamine was subsequently selected for human trials, and the first human anesthetic dose was administered on August 3, 1964 by two University of Michigan professors: Dr. Edward Domino and Dr. Guenter Corssen.
They found that ketamine could rapidly produce profound analgesia with a unique state of altered consciousness and a limited duration of effect. They also reported minimal side effects and a lack of severe emergence delirium compared to phencyclidine (Corssen and Domino, 1966). Ketalar (1970) became the first preparation of ketamine approved by the food and drug administration (FDA) for human use.
*Reproduced from a pubmed article found here
5 Lessons
Curious about Ketamine: An overview
Ketamine is a synthetic drug discovered in the 1960s. Initially used as an anesthetic, Ketamine has become popular for a whole host of reasons.
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*Please take note: This module is for general educational purposes only. Jennifer Boyd is a Physician Associate licensed in the states of CT and NY. You are required to have your own licensed medical provider to help you manage your health.